Wingnut,
I can assure you that it's not necessarily the case that a resin copy of a copy will be of inferior quality - but it often does happen that way.
It all depends on the condition of the part and how well its molded.
I've been making masters and casting resin parts for many years, and I can tell you that RTV molds can (and do) provide a PERFECT negative image of the original - even down to duplicating dusty fingerprints!
As long as care is taken, the first duplicate off of the copy should be pretty perfect - but due to poor technique or materials, home casting often produces sub-par copies of copies. Having a vacuum chamber and using very soft RTV produces excellent results, but a chamber isn't easy to come by.
If you plan on making only a few copies, then make one mold and cast from that mold. If you plan on making 20 or 30, then use the MASTER to make a whole bunch of molds - that way, all of your resin copies are copies of the master - not of a copy. Get it?
Good luck, mate.