I've been experimenting with PE for the better part of a year now, trying to find what works best.
I've found the best way to get it off the sprue is with a #11 blade. All the eduard PE sprues I've come across are packed too tightly together to get the shear tips in there. To nip the itty bitty parts that are left, I cut them off with a plastic sprue cutter. It has a flat bottom for making flush cuts.
To pick up the tiny PE parts, I use Pick n' sticks. They're like one-sided q-tips, but instead of cotton, it has wax. It sticks to everything, but releases easily. In the 8 months or so I've been using them, I've gone through just about 4 sticks (I think they are packs of 8, like a book of matches). They're reusable, so every once in a while, I reshape the wax and it's like a whole new stick.
For bending, I have to say, I just started using a tool called The Bug - and boy, does it make a difference. I'm getting bends I could never get with my tweezers, pliers and razor blade. It's a little pricey at $40, but it's definitely worth it.
-Fred