I use Bondo Red Glazing Putty (auto parts stores) and Testor's Contour Putty...
One of the main things I do is thin the putty... This will cut down you sanding times... I thin the Bondo with Testor's liquid cement (pink label) and the Testor's gets cut with rubbing alcohol...
Also, putty shrinks as it dries, so use a little more than you think you need, and ALWAYS wet-sand putty... Applying it in layers, helps speed drying times as well.. When I fill a seam like a fuselage joint, I just run a bead of Testor's putty down the length of the seam (No more than three or four inches though... Take your time.. ) Then I push into place with a gloved finger (sometimes).. Dipping the finger in alcohol thins the putty, and allows you to push it into the gaps, not just cover over it.. Smooth it as much as possib;e with the "Thinnered" finger, wait for it to dry, then give a few good swipes with the sanding film... Then apply another thin, thinned, layer, using a spreader cut from sheet styrene, and feather it out... Let it dry, then feather-edge it with the wet-sanding again...