That is only if you are sanding it and raising a huge dust cloud in an enclosed room, such as sanding sheetrock joints. Joint compound is basically gypsum and water, both natural materials. The Chinese stuff has many unknown chemicals in it so stay away from that stuff.
WIP: Monogram 1/72 B-26 (Snaptite) as 73rd BS B-26, 40-1408, torpedo bomber attempt on Ryujo
Monogram 1/72 B-26 (Snaptite) as 22nd BG B-26, 7-Mile Drome, New Guinea
Minicraft 1/72 B-24D as LB-30, AL-613, "Tough Boy", 28th Composite Group