Ok well you can really go either way here. I would use a base color close as possible to the color you want to end up with,even a primer tinted to an orange would be good. Or just a close color. You might should try a couple different colors on an old car body or something first. The effect you want may be different than what i would do. The pearl colors tend to be a little transparent so multiple thin coats may be needed. So do say ..one fender with an orange then another in silver over a primer. Then try your pearl. Keep in mind that after you do a final clear coat it will look a little different. I hope this helps. Ohh yeah make sure you let each coat dry a day or two before you add another over it.
If this is confusing let me know and ill try to make it more clear.