You are right, this is interesting!
Could have been your primer, I guess, but presumably you had used it before. I've had very good luck with Tamiya primer, as I mentioned, and I don't do anything special. Spray it, let it dry a couple of hours, do whatever I want to on top of it.
That primer is very "Hot" though, so it cures (or at least "Dries") pretty quickly. I usually spray it outside, and by the time I get back to my bench I can see it drying to the touch. A couple of hours in front of a fan seems to be all it takes.