I'm going to assume that your question is asking "do you mix in a separate container" rather than "do you have to thin your paint" before putting in your airbrush.
I prefer to mix my paints in a steel measuring spoon (no particular reason for the spoon, other than it's available and convenient) before pouring it into my airbrush cup. I prefer to mix it "outside" the airbrush because paint consistencies vary from one jar to another and I like to see how it flows before it goes into my airbrush.
When I used to use a siphon feed brush, I mixed directly in the paint jar.
If indeed you are asking "do you thin your paint", the answer is yes. Most model paints are too thick to airbrush "straight". Even though there are some which can be airbrushed without thinning (eg. Gunze acrylics, Vallejo "Model Air") these paints do benefit (smoother finish) from a little thinning.