All good advice so far.
As for laying down a thin layer first - i used to lay down, essentially, a full layer of gray paint as a primer.
I've now switched to super fine tamiya primer from a spray can as i find it's much easier to use and goes down beautifully.
In terms of how many layers you can put down and drying time - that's up to the paint. I use acrylics which have alcohol in the thinners, so they are touch dry in a matter of minutes, however, i normally wait 24 hours before putting anything over them - there is a difference between a paint drying and paint curing - i'm not sure of the chemcal reactions etc, but to be safe, i wait 24 hours.
The same with tamiya primer - i think it's lacquer based and it take a bit longer to dry than acrylic paint. I'll let it dry for 24-48 hours before painting over it.
When you're painting with a colour (once all priming down), i'll normally build up slowly, in that, i paint the area with multiple passes all in the one session. Ie, i don't do a single pass, wait for it to dry, come back for another single pass etc. Normally, it could take 4-6 passes to build up a sufficient layer that i'm happy with.
Whatever you do though, keep the brush moving to avoid puddles and runs.
Any other questions, feel free to ask away.
Good luck and have fun!