They are much harder to clean than acrylics. Nothing beats water cleanup. If you are a beginner I suggest use acrylic paints. They are the future in this hobby. The advantages of easy cleanup and lack of fumes far out weigh any disadvantages. In fact if you are only going to be brush painting then I would say there is no disadvantage in acrylics.
The hobby enamels for models are easy to use. The only thing is that is requires solvents to clean and are more hazardous to your health. Depending on the state of California they might even disappear. If California decides to ban them then I'm sure all the manufacturers will only sell acrylics. If you don't believe this, then take a look at the hobby lacquer paints that used commonly available.