Mike,
They may be water-based, but once sprayed, any ethers, alcohols, or other waterborne solvents are going to vaporize; therefore, the necessary protection is going to be an organic vapor respirator. You're still going to get some water and pigment, so a good prefilter should work to catch that as well. Continue wearing your MSA half mask, Mike.
Understand that this is totally dependent on the manufacturer-specific ingredients. Some of the acrylics may be TOTALLY water-based, and therefore, a paper mask would probably suffice; however, there are the other ones that use alcohol or other water soluble solvents--like some alcohols.
Without having a complete MSDS library at your disposal for all this stuff, my advice is that if, during the spraying operation, you smell something funky, or if you start feeling lightheaded, nauseated, etc., or if you are simply unsure what's in the stuff and have become justfiably paranoid (
), slap on a good respirator, vent the room, and spray away.
Help some?
Gip