The 2128 cartridge you are referring to is a "combination" cartridge--that is it includes a particulate filter for dusts, mists, and fumes, and treated activated charcoal that not only removes organic vapors, but also removes acid gases. While it is (usually) a more expensive filter, it is more convenient to use than an organic vapor cartridge and its attendant prefilter(s). I don't think that $10 is too much to pay for what you're getting. In addition, the 2128 is designed to fit the older 6000, and newer 7500 series respirators. Depending on your painting habits, controls (room fans, open windows, etc), and how you treat your respirator after painting sessions are complete will determine how long the cartridges last. Based upon professional judgement and personal experience, I would expect your cartridges to last a LONG time before replacement is necessary. Of course, any time you smell contaminants through the respirator, or have difficulty breathing (given a good face-to-facepiece seal), you should consider changing the cartrigdges.
Merry Christmas!
Gip Winecoff