In general, yes, the time between "light coats" can be substantially reduced compared to multiple "normal" coats. Your specific time between coats depends greatly on the medium you're spraying. When I'm shooting Future, I'll wait 10 to 15 minutes between light coats. With MM enamels, I usually begin spraying a second light coat almost immediately following the completion of the first coat. I cannot speak to acrylic paints since I've never used them. However, with both the Future and enamels, I've never had a significant problem with the airbrush being affected by 10 to 15 minute pauses between coats. My general rule of thumb is if I'm not going to shot additional coats of any medium within 20 minutes maximum, the airbrush gets cleaned. That's just my rule and others may vary.
BTW, Welcome to the forums!!!