Hey MKMT,
Slow down, buddy, you're overthinking this project. You're going to make it waaay more complicated than it has to be. There's no need for extra fuses and there's no concern of cross draw or extra ventillation.
The nice part of my design was that it was simple and flexible. Here's a step by step rundown that can hopefully paint a more clear picture of what I was doing. Just make sure to read the directions all the way through first. Some steps may be easier to do before the box is assembled, so use your judgement.
1) build a sheet steel box, 25Wx18Hx18D and mount it to a piece of plywood. The plywood base should at be as wide as the box, but definitely deeper (figure around 25-26"). This extra space will be for the backside so you can mount the blowers and the power supplies.
2) 2" from the rear of the box add another sheet of the steel (like a false back plate) perferated by 1/2" holes - this is the baffle plate and helps to normalize the airflow before it gets to the blowers (and your filter sits in front of this plate on the inside of the work area)
3) In the back plate of the box, cut out (2), 4" dia. circles so that they are centered in the plate (about 4" between the two cutouts). This is where you're 2 blowers will mate to the box.
4) You'll need 2 sections of 4" i.d. duct connectors (one per blower). This is how you mount the blower to the box. One side of the duct connectors is going to slide over the blower intake and get clamped in place. The other side of the duct needs to be cut and splayed. Think of making one side look like a daisy. This side is getting attached to the box. Drill a hole in each of the flaps and then line it up so the duct makes a sleeve with hole in the back plate. Use a permanent marker to mark the back plate where the holes in the flaps would be in the back plate. Now you can either drill them out so you can bolt them together or my favorite, use pop rivets - clean, simple and effective. Now do this for the other blower mounting.
5) Now that the blower sleeves are attached, you can slide the blowers in place and make marks in the base board so you can drill pilot holes for the mounting screws. Drill your holes and slide your blower into position (don't forget to put the clamp in place first). Now see where you're going to mount the power supplies. Wire up your blowers, then attach the PSs and the blowers to the base board.
6) Get 2 lengths of 4"x8' flexible dryer duct. Attach one per blower using a 4" hose clamp. Other end just hangs out the window
7) get one (or a few) of those self mounting, battery powered lamps so you have some light to work with, a furnace filter and you are finished.
Now you can run one or both of your blowers depending on what you want to do. If you're venting while painting, run 2. If you're venting while drying, run 1. That's the beauty of my design - simplicity and functionality
-Fred