Most certainly. Always test on a scrap piece first before using a new (to you) paint, but many hardware store spray paints can be used on plastic & resin models. Remember to go slow -- several light coats are better than one thick one.
You may find it interesting that Testors paint is (or was) owned by the same company as Rustoleum paint, RPM Industies.
Don't limit yourself to only buying hobby supplies with a model manufacturer's logo. You will find a broad supply of material, often at a significant price differential.