First never let a TnF sit for prolonged periods with solvent inside. At the end of your building session blow into the glass end to push any remaining solvent out through the needle. This will flush the TnF clean.
Soaking the needle end of a TnF in the solvent you are use will clear the end of the needle (which is usually where the clogs occur) applicator 99% of the time. Refrain from "pushing" the needle along the surface when you are applying solvent. Always "pull" away leaving a trail of solvent behind.
In the worst case senario when the needle is hopelessly clogged, one can insert a piece of fine wire into the glass end, down into the needle applicator to push out the debris. NEVER push the debris from the needle into the glass, you'll soon find out you are clogged yet again.