Resin isn't all that intimidating once you work with it for awhile.
First, when cutting or sanding pieces from the resin block, use a respirator. Or your shirt or anything that will keep resin dust from being inhaled. From what I understand it's not good stuff for the old lungs.
Second, when you are removing pieces from the blocks, try running the x-acto blade across the resin attachment to score it. The piece can usually just be snapped loose at the score line. It really just depends on the piece and how it's attached to the resin block. I've had big pieces where I used a small saw to detach the piece and then spent several days sanding down the rest.
Third, standard super glue that melts plastic together will not work with resin. You'll need to use CA glue or epoxy.
Fourth, painting resin is not any different than painting plastic. I prime it and paint just like anything else.
Good luck!