On armor, or really filthy aircraft, a wash over the whole model is fine to both accentuate recesses and to show the accumulation of dirt and grime on the surface. If you don't want that overall grimy look, then you might want to avoid an overall wash.
Personally, I always brush-wash the whole thing (talking armor here) with a dark 'n' nasty "sludge wash." Wiping it off is part of the technique, as you can recreate realistic rain streaks and other grunge effects. The one thing to be careful of is pooling, which can lead to unrealistic effects (or realistic effects, depending on how you manipulate the flow) as the wash dries.
Also, to get the grungy, dusty effect I like, I apply the wash over a flat finish, rather than glossy (which most people seem to prefer, particularly for aircraft). I also use acrylic enamels for my washes.
I would avoid using an airbrush, for the reasons eloquently stated above. But who knows, you might come up with a technique you like!
Happy washing!