I always prime unless I am doing a cockpit interior or wheel wells which won't be masked. My experience is that Model Master priming is a requirement as it has poor adhesion over bare plastic. I did the wheel wells of my last 109 without priming using Vallejo Model Air acrylics and I tested the overspray on the wings with both Tamiya and Scotch Blue tapes and neither pulled it up. No real experience with Tamiya as I only have used it on armor which I always prime.
I use Vallejo's acrylic polyurethane primers. I have three colors; grey (which dries almost white), panzer dark grey and black. You can mix them to get whatever shade of gray you need.
Better safe than sorry would be my recommendation. As others have said, priming is useful in reviewing your work before the final coat(s).
John