I was just mulling over the same question to myself. Fortunately I found this thread. Looks like I'll go ahead and prime.
BTW, I'm using Tamiya acrylics plus at least two other types depending on the colors - (Vallejo Metal Color - aluminum, Vallejo Model Color - silver, and Model Master - wood).
I've thoroughly washed the sprue trees. In the past I've mostly just skipped the priming but I'm waiting for some aftermarket stuff on my 1/48 Supermarine Walrus from Airfix so I might as well spend some down time constructively.