I'm going to reply with a disclaimer. My use of metalizers has thus far been limited to small things and I haven't had any issues. That said, in theory . . .
Yes, a primer should help. Metalizer I noticed doesnt cut good with mineral spirits but does with lacquer thinner. I assume from that + odor that it's a lacquer base, which makes the most sense to me. Lacquers dont tend to like plastic much. While I'm sure that they've done what they can formula wise to overcome this, anything you can do to give it something better to bite on, like an enamel, should go far.
Now that you've posed this question I have an experiment I think I'll try tomorrow with some spare plastic. I use a vinyl based lacquer sealer in furniture when I'm dealing with woods that have natural oils (very few - rosewood, cocobolo) that will bond to almost anything. I ought to try shooting that on plastic and see if it bites or if its too hot and just melts it.